Melrose Real Estate

Melrose Real Estate

Welcome to Melrose, a charming and picturesque subdivision nestled in the heart of Putnam County, Florida. Known for its serene landscapes and friendly community, Melrose offers a unique blend of rural tranquility and modern convenience, making it an ideal place to call home.

As you stroll through the tree-lined streets of Melrose, you'll be captivated by the stunning natural beauty that surrounds you. The area is dotted with lush greenery, sparkling lakes, and scenic parks, providing ample opportunities for outdoor activities such as fishing, boating, and hiking. Residents often gather at local parks for picnics, family outings, and community events, fostering a strong sense of belonging and camaraderie.

Melrose boasts a variety of charming homes, from cozy cottages to spacious family residences, catering to diverse lifestyles and budgets. The real estate market here is vibrant, with properties that often feature large yards and access to serene waterfront views. Whether you are a first-time homebuyer or looking to settle down in a peaceful setting, Melrose has something for everyone.

In addition to its natural allure, Melrose is conveniently located near essential amenities, including grocery stores, schools, and medical facilities. The nearby city of Gainesville offers additional shopping, dining, and entertainment options, providing residents with the best of both worlds.

Experience the warmth and charm of Melrose, where every day feels like a retreat. Discover your dream home in this idyllic community and embrace a lifestyle filled with nature, community spirit, and tranquility. Welcome home to Melrose, Florida!

Newest Listings in Melrose

$79,900
2158521 MLS
Rare Vacant Lot in the heart of Charming Historic Downtown Melrose Florida. With its cozy Small Town personality Melrose is peacefully inviting and a melting pot for all. Come and experience This lot is one of the last chances to own a piece of paradise. The lot is mostly cleared and has a updated SURVEY already done. All .44 acres are Hi & Dry, partially fenced and is adorned, Live Oaks, Bahia Brass and Florida Palm Trees. Positioned right in the Heart of Downtown Square your just blocks away from Nightly Live Music, Fresh Food Markets, Multiple Art Galleries, family friendly parks, World Class Restaurants and walking distance to OUR NEW 240 ACRE WILDFLOWERS MUSIC PARK!! The all Stunning Melrose Bay with public parks. The Bay is attached to Majestic Lake Sante Fe! 6,000 acres where you can enjoy Sunsets, Kayaking, fishing, wake surfing, tubing, skiing, and even Sailing. Melrose is only 20 minutes to Gainesville, 25 minutes to Palatka and 30 minutes to Ocala. Drive-''Buys''are welcome

404 Grove Street, Melrose
$495,000
3 Beds ⋅ 2 Baths ⋅ 2156999 MLS
Welcome to Lilly Lake, where peaceful lakefront living meets stylish modern comfort. Nestled on the crystal-clear, spring-fed waters, this fully upgraded 3-bedroom, 2-bath home offers the perfect retreat from the hustle and bustle of city life. Step inside to a bright, sun-filled interior featuring luxury vinyl flooring throughout, a cozy wood burning fireplace, and tasteful designer finishes that create a warm yet elegant atmosphere. Every detail has been thoughtfully updated, making this home truly move-in ready. The outdoor living space is just as impressive. A spacious lakefront deck provides the perfect setting for entertaining guests, enjoying morning coffee, or simply taking in the breathtaking views. Down by the water, you'll find your own private boat ramp, boat lift, and an elevated sitting area-ideal for watching sunsets or relaxing by the lake. If you've been dreaming of peaceful waterfront living with modern upgrades and year-round recreation, this is the perfect home.

8443 Lily Lake Road, Melrose
$550,000
3 Beds ⋅ 2 Baths ⋅ 2155169 MLS
Escape the hustle and embrace the peaceful country lifestyle on this beautiful 5-acre retreat, surrounded by mature pecan trees, and thoughtfully designed for both comfort and functionality. Ever dreamed of raising chickens, goats, pigs, horses, or creating your own private homestead? This exceptional property offers the space and freedom to make it a reality. Home is completely move-in ready, with modern finishes throughout. Updated kitchen with new appliances and cabinetry. New laminate floors, fully renovated bathrooms and fresh paint inside and outside. Whether you want to plant a garden, bring your RV and recreational toys, or simply relax beneath the shade of the gorgeous pecan trees, this is it! Ideally located less than 1½ hours from Jacksonville and approximately 2 hours from either Orlando or Tampa, you'll enjoy the serenity of country living without sacrificing access to Florida's major cities, world-famous attractions, shopping, dining, airports, and beautiful beaches.

19211 Ne State Road 26, Hawthorne
$180,000
2153434 MLS
Escape to your own private slice of Old Florida on this beautiful 10 acre high and dry lot tucked away on Lady Bug Lane in Melrose. Surrounded by larger acreage parcels, native woods, and open farmland, this property offers the rare combination of true seclusion without sacrificing convenience. Untouched natural beauty creates a breathtaking setting filled with wildlife and peaceful country living. Whether your vision is a custom cabin in the woods, mini-farm, or weekend retreat, this property gives you the freedom to build the lifestyle you want. All this yet just 5 minutes from Twin Lakes Park and less than 20 minutes from numerous lakes, boating, fishing, parks, and outdoor recreation options. If you've been searching for space, freedom, and the opportunity to enjoy country living the way it was meant to be, this is it!

0000 Lady Bug Lane, Melrose
$375,000
10 Beds ⋅ 3 Baths ⋅ 2151666 MLS
The historic Lee House at 200 Park Street in Melrose, was built in 1879 by William Lee as his personal residence. As his family grew he expanded the structure into a sprawling 27 room property. During the 1920 & 30's it operated as a prominent boarding house and remained in the Lee family for over 100 years. The room count in mls may be off because not all bedrooms have closets and there are some two room bedroom or double rooms.

200 Park Street, Melrose
$135,000
2144479 MLS
Opportunity awaits with this 2.97-acre commercial property offering a cleared and fully fenced parcel with gated access already in place. The property features an installed culvert at the entrance for convenient access and added functionality. Zoned C1 with current usage zoned RR, this versatile property presents a variety of potential possibilities for future development. Located on a well-traveled highway that is an easy commute to Melrose, Keystone Heights, Interlachen, Gainesville and Palatka. Buyer encouraged to perform all due diligence regarding zoning, permitted uses, and intended usage. No utilities on property.

1551 State Road 100, Melrose
$140,000
3 Beds ⋅ 2 Baths ⋅ 2140192 MLS
This property consists of two separate parcels totaling 6.8 acres--nearly 7 acres that immediately set it apart, offering space, privacy, and long-term potential. The home itself will require updates and improvements, but it provides a solid starting point for someone looking to reshape or reimagine the property over time. What makes this offering compelling is the balance between the existing structure and the land value. With this much acreage, the opportunity goes far beyond the current footprint. This is a property for someone with vision--ready to create something more intentional in a setting that actually allows it.

1056 Bellamy Road, Melrose
$330,000
4 Beds ⋅ 3 Baths ⋅ 2136558 MLS
Step back in time while enjoying modern possibilities with this beautifully preserved historic home, originally built in 1885 by Henry Baldwin of Naugatuck, Connecticut. Nestled in the heart of picturesque Melrose, Florida, this two-story residence offers a rare blend of heritage, charm, and versatility.Featuring 4 bedrooms and 2.5 bathrooms, the home boasts classic architectural details and inviting living spaces filled with warmth and character. Relax and unwind on the front or back porches, perfect for enjoying Florida's tranquil surroundings, morning coffee, or evening gatherings.The property also includes a quaint metal-roofed workshop, brimming with potential--easily convertible into a charming guest cottage, studio, or creative retreat. There is also another small out building perfect for storage.Adding to its appeal, the property is zoned for home-based business use, offering a unique opportunity. Seller is open to owner financing.

25415 Ne Sr 26, Melrose
$119,900
2115837 MLS
RIGHT IN THE HEART OF HISTORIC MELROSE FLORIDA WE HAVE A VERY RARE TO FIND VACANT OVERSIZED BUILDABLE LOT. THE PROPERTY IS ONLY 1 BLOCK FROM THE PRISTINE 6,000 ACRE SANTA FE LAKE THAT I CALL '' THE GREAT LAKE OF NORTH CENTRAL FLORIDA ''. HISTORIC MELROSE WAS ESTABLISHED 1877. OLD HISTORIC HOMES ALL NEAR THIS BEAUTIFUL WOODED LOT. WHEN YOU ARRIVE HERE - YOU'LL WANT JUST PARK AND TAKE A WALK AROUND THIS AMAZING LITTE ONE LIGHT TOWN. VISIT MELROSE BAY PARK JUST AROUND THE CORNER FOR SOME SWIMMING OR LAUNCH YOUR KAYAK JUST ONE BLOCK AWAY IN THE NO WAKE ZONE AREA OF MELROSE BAY. IN BIG SANTA FE YOU CAN ALSO ENJOY WAKE BOARDING, FISHING, PADDLE BOARDING, SKIING, SAILING AND MORE. MELROSE IS KNOWN FOR IT'S RICH CULTURAL COMMUNITY, ART IN MANY MEDIUMS, MUSIC, CRAFTS, LOCAL PRODUCE, SENIOR CENTER SERVING FOOD, SHOPPING, DOCTORS, DENTIST, ART GALLERIES, MUSIC EVENTS AND MORE. MELROSE IS AN EASY COMMUTE TO GAINESVILLE, PALATKA, THE BEACHES, OCALA, STARKE, KEYSTONE, AND MIDDLEBURG. IF YOUR WANTING A DIFFERANT WAY OF LIFE OUT HERE IN RURAL AMERICA, THEN DRIVE OVER, LOOK AROUND, CHAT WITH A FEW FOLKS AND SEE THIS AMAZING HISTORIC TOWN THAT JUST SEEMS TO HAVE IT ALL. YOU'LL BE WELCOMED. PS:THE SECOND TIME YOU COME BACK TO MELROSE YOU'LL WANT TO BRING YOUR CONTRACTOR. NOTE: POSSIBLE OWNER FINANCING MAY BE AVAILABLE?

LOT 18 Trout Street, Melrose
$949,000
GC520243 MLS
The Melrose Center consists of two to of the most attractive buildings located in the heart of Melrose. The buildings represent a limited selection of commercial property that faces the main thoroughfare of Hwy 26, a major roadway running from Gainesville to Putnam Hall Fl. The front building, “The Studios of Melrose” consists of eleven mixed use offices ranging from health care providers to artist studios, to a multi-room art gallery. The building represents the Victorian four-square design that is a historic standard throughout the town. The Center is licensed as a fifty-seat full service restaurant with both inside and outside eating areas. The kitchen was fully renovated in 2021, with much of the equipment upgraded to brand new condition. The facility has both inside and outside stages which are used to showcase musicians on a weekly basis. The inside hall is also used to showcase local artists’ work. Certified by Visit Florida The Welcome and Information Center is officially certified by Visit Florida—a recognized State of Florida designation. It serves the broader Lake Area Region spanning Gainesville, Ocala, Palatka, St. Augustine, and Jacksonville, and is affiliated with all statewide Welcome Centers through Visit Florida. Unmatched Visibility Located between I-75 and I-95, this site sees 8,000–10,000 cars daily. It's not any ordinary spot – it's a combination restaurant, art house, and community gathering place. If you've ever dreamed of owning a place where food and art come together - the Melrose Center might just be your perfect opportunity.

307/309 State Road 26, Melrose
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The data relating to real estate for sale on this web site comes in part from the Internet Data Exchange (IDX) program of the Northeast Florida Multiple Listing Service, Inc. Real estate listings held by brokerage firms other than Realty Exchange LLC are marked with the listing broker’s name and detailed information about such listings includes the name of the listing brokers. Data provided is deemed reliable but is not guaranteed. © 2026 Northeast Florida Multiple Listing Service, Inc. All rights reserved. Data last updated